Calcitriol-mediated Reversible Hypercalcemia in a Patient with Primary Adrenal Lymphoma.

نویسندگان

  • Shahnaz Ahmad Mir
  • Shariq Rashid Masoodi
  • Arshad Iqbal Wani
  • Syed Nisar Ahmad
  • Iqra Hameed
چکیده

Primary adrenal lymphomas (PAL) are rare occurrences with only less than 150 cases reported in the literature. Two-thirds of these cases were reported in the last decade due to the advancements in imaging techniques and immunohistochemistry. The non-specific signs and symptoms have resulted in a delayed onset of symptoms and diagnosis of these tumors. Reports of the results of chemotherapy are not gratifying, and most patients die within one year of the diagnosis. We report a 65-year-old male with adrenal non-Hodgkin's lymphoma (NHL), who presented with hypercalcemia and renal failure. We reviewed all adrenal NHL cases presented with hypercalcemia and attempted to comprehend its etiology and overall survival effect.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Calcitriol-mediated hypercalcemia in a patient with bilateral adrenal non-Hodgkin's B-cell lymphoma case report.

Calcitriol-mediated hypercalcemia is a frequent manifestation of hematological malignancies. However, there are a few reports of cases presenting with increased angiotensin-converting enzyme (ACE) level, which suggests a possible mechanism similar to that of granulomatous diseases. We present a patient with hypercalcemia, normal parathyroid hormone, and parathyroid hormone-related protein level...

متن کامل

Hypercalcemia and large abdominal mass

An 85-year-old woman with chronic renal insufficiency presented with appetite loss and abdominal fullness. Laboratory data showed serum creatinine levels of 5.46 mg/ dL, urea nitrogen 42 mg/dL, corrected calcium 15.3 mg/ dL, intact PTH parathyroid hormone 15.1 pg/mL (N 10– 65), calcitriol 63.4 pg/mL (N 20–60), PTH-related protein 5.5 pmol/L (N < 1.0), cortisol of 4.3 pg/mL (N 6.2–19.4), ACTH ad...

متن کامل

Hypercalcemia in Lung Cancer due to Simultaneously Elevated PTHrP and Ectopic Calcitriol Production: First Case Report

Calcitriol-mediated hypercalcemia has been reported in malignant lymphomas and granulomatous diseases but not in lung carcinoma. We describe a patient with squamous cell lung carcinoma with hypercalcemia and elevated calcitriol levels. A 60-year-old Caucasian male patient with stage IIIB squamous cell lung cancer developed hypercalcemia at 14.8 mg/dL two years after receiving chemotherapy and r...

متن کامل

Hodgkin's Disease and Non-Hodgkin's Lymphomas

DISTINCT SYNDROME of calcitriol (1,25-dihyA droxyvitamin D,)-mediated hypercalcemia is seen in patients with Hodgkin's disease and non-Hodgkin's lymphomas (NHL). In addition to hypercalcemia, this syndrome is characterized by intestinal hyperabsorption of calcium, normal serum phosphate levels, the absence of renal phosphate wasting, and increased renal excretion of calcium. Other characteristi...

متن کامل

Calcitriol: the major humoral mediator of hypercalcemia in Hodgkin's disease and non-Hodgkin's lymphomas.

DISTINCT SYNDROME of calcitriol (1,25-dihyA droxyvitamin D,)-mediated hypercalcemia is seen in patients with Hodgkin's disease and non-Hodgkin's lymphomas (NHL). In addition to hypercalcemia, this syndrome is characterized by intestinal hyperabsorption of calcium, normal serum phosphate levels, the absence of renal phosphate wasting, and increased renal excretion of calcium. Other characteristi...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • The Malaysian journal of medical sciences : MJMS

دوره 23 6  شماره 

صفحات  -

تاریخ انتشار 2016